📍 Job Overview

• Job Title: Senior/Principal Clinical Database Manager
• Company: Precision Medicine Group
• Location: Remote (UK, Spain, Hungary, Poland, Romania, Serbia, Slovakia)
• Job Type: Full-time
• Category: Clinical Data Management
• Date Posted: 2025-08-01
• Experience Level: 5-10 years
• Remote Status: Remote (Solely)

🚀 Role Summary

• Lead the design, development, and maintenance of clinical databases and applications.
• Collaborate with internal teams, clients, and vendors to gather requirements and provide status updates.
• Train end-users and junior staff on operational and technical aspects.
• Contribute to internal software projects requiring specialized programming or scripting.
• 📝 Enhancement Note: This role requires a strong technical background in clinical data management, with a focus on database development and programming. It also involves significant stakeholder communication and leadership.

💻 Primary Responsibilities

• Database Management: Design, develop, test, implement, maintain, and support clinical databases and applications.
• Stakeholder Communication: Interface with internal teams, clients, and vendors to gather requirements and provide status updates.
• Training: Provide operational and technical training to end-users and junior staff.
• Project Contribution: Contribute to internal software projects requiring specialized programming or scripting.
• 📝 Enhancement Note: This role requires a balance of technical expertise in database management and strong communication skills to effectively collaborate with various stakeholders.

🎓 Skills & Qualifications

Education: Bachelor’s degree or a combination of related experience.

Experience:

• Proven experience in developing and customizing clinical data management databases.
• Background in a clinical, scientific, or healthcare discipline.
• Experience with Rave API integration and Advanced Custom Function programming.

Required Skills:

• Proficiency in Microsoft Office: Word, Excel, PowerPoint, Outlook.
• Excellent organizational and communication skills.
• Professional use of the English language, both written and oral.
• Experience in Object Oriented Programming (C#, C++, VBS, etc.), scripting language (PERL, etc.), SAS, R, SQL.
• Understanding of CDISC standards (CDASH, SDTM, ADaM, etc.).
• Experience in clinical database management system development.
• Broad knowledge of drug, device, and/or biologic development and effective data management practices.
• Strong leadership and interpersonal skills.

Preferred Skills:

• Oncology and/or Orphan Drug therapeutic experience.
• Base SAS®, SAS/STAT and SAS/ACCESS software.
• SAS Macro programming language.
• Advanced experience in Database Management, object-oriented programming.
• Veeva set up experience.

📊 Web Portfolio & Project Requirements

Portfolio Essentials:

• Demonstrate experience in developing and customizing clinical data management databases.
• Showcase proficiency in programming languages and understanding of CDISC standards.
• Highlight experience in clinical database management system development.
• 📝 Enhancement Note: As this role focuses on clinical data management, the portfolio should emphasize database development projects and case studies demonstrating the candidate's technical expertise and problem-solving skills.

Technical Documentation:

• Provide documentation on database development processes, including design, testing, implementation, and maintenance.
• Include examples of status updates and communication with stakeholders.
• 📝 Enhancement Note: The technical documentation should showcase the candidate's ability to manage complex projects, collaborate with stakeholders, and ensure data quality and integrity.

💵 Compensation & Benefits

Salary Range: £55,000 - £75,000 per annum (based on UK market rates for similar roles in clinical data management)

Benefits:

• Competitive benefits package, including health, dental, and vision insurance.
• Retirement savings plan with company match.
• Generous time off and flexible work arrangements.
• Employee assistance program.
• 📝 Enhancement Note: While the salary range is based on UK market rates, the benefits package may vary depending on the candidate's location and local regulations.

Working Hours: Full-time (40 hours per week), with flexibility for project deadlines and maintenance windows.

🎯 Team & Company Context

🏢 Company Culture

Industry: Precision Medicine Group specializes in revolutionizing cancer treatment by combining deep science, advanced technological platforms, and specialized expertise in clinical trials.

Company Size: Precision Medicine Group is a mid-sized organization, providing opportunities for growth and career development within a collaborative and innovative environment.

Founded: 2005 (as a subsidiary of UDG Healthcare plc)

Team Structure:

• The clinical data management team consists of database managers, data managers, and junior staff.
• The team works closely with internal stakeholders, including data management, project management, and clinical operations.
• 📝 Enhancement Note: The team structure encourages collaboration and knowledge sharing, with opportunities for mentoring and professional development.

Development Methodology:

• Precision Medicine Group follows Agile methodologies for project management and software development.
• The team uses version control systems (e.g., Git) and collaboration tools (e.g., Jira) to manage projects and track progress.
• 📝 Enhancement Note: The development methodology emphasizes iterative development, continuous improvement, and cross-functional collaboration.

Company Website: Precision Medicine Group

📈 Career & Growth Analysis

Clinical Data Management Career Level: This role is at the senior/principal level, requiring a high degree of technical expertise and leadership. The candidate will be responsible for managing projects, mentoring junior staff, and driving process improvements.

Reporting Structure: The Senior/Principal Clinical Database Manager will report directly to the Director of Clinical Data Management and will oversee junior database managers and data managers.

Technical Impact: The role has a significant impact on the quality and efficiency of clinical data management processes, ensuring data integrity and compliance with CDISC standards. This, in turn, influences the success of clinical trials and the development of new therapies.

Growth Opportunities:

• Technical Growth: Expand expertise in programming languages, database management systems, and CDISC standards.
• Leadership Development: Develop skills in team management, project leadership, and strategic decision-making.
• Career Transition: Transition into a more specialized or senior role within the organization, such as a Director or Vice President of Clinical Data Management.
• 📝 Enhancement Note: Growth opportunities are tailored to the individual's skills, interests, and career goals, with a focus on continuous learning and professional development.

🌐 Work Environment

Office Type: Precision Medicine Group operates a hybrid work environment, with both on-site and remote work options available.

Office Location(s): The company has offices in the UK, US, and Europe, with remote work opportunities available for eligible candidates.

Workspace Context:

• Remote Work: Remote workers can expect to have access to the necessary tools and resources to perform their job effectively, including a laptop, software licenses, and secure remote access to the company's network.
• On-Site Work: On-site workers can expect to have access to collaborative workspaces, meeting rooms, and breakout areas.
• 📝 Enhancement Note: The work environment is designed to support collaboration, innovation, and work-life balance, with a focus on employee well-being and engagement.

Work Schedule: Full-time (40 hours per week), with flexibility for project deadlines and maintenance windows. The work schedule may vary depending on the candidate's location and local regulations.

📄 Application & Technical Interview Process

Interview Process:

• Screening Call: A brief call to discuss the candidate's background, experience, and fit for the role.
• Technical Deep Dive: A detailed discussion of the candidate's technical skills, focusing on database management, programming, and CDISC standards.
• Stakeholder Simulation: A role-play exercise simulating interactions with internal stakeholders, clients, and vendors.
• Final Interview: A discussion of the candidate's career goals, cultural fit, and final questions.
• 📝 Enhancement Note: The interview process is designed to assess the candidate's technical expertise, communication skills, and cultural fit within the organization.

Portfolio Review Tips:

• Project Selection: Choose projects that demonstrate the candidate's experience in clinical data management, database development, and programming.
• Case Study Structure: Organize projects into clear, structured case studies, highlighting the problem, solution, and outcome.
• Technical Documentation: Include detailed technical documentation, demonstrating the candidate's ability to manage complex projects and ensure data quality and integrity.
• 📝 Enhancement Note: The portfolio should showcase the candidate's ability to manage complex projects, collaborate with stakeholders, and ensure data quality and integrity.

Technical Challenge Preparation:

• Database Design: Brush up on database design principles, including normalization, indexing, and optimization.
• Programming: Review programming languages and scripts relevant to the role, such as SQL, SAS, and R.
• CDISC Standards: Familiarize yourself with CDISC standards, including CDASH, SDTM, and ADaM.
• 📝 Enhancement Note: The technical challenge will focus on the candidate's ability to design, develop, and maintain clinical databases, as well as their understanding of CDISC standards and programming languages.

ATS Keywords: [Clinical Data Management, Database Development, Programming, Scripting, CDISC Standards, Stakeholder Communication, Leadership, Oncology Experience, Veeva Setup, Advanced Custom Function Programming, Rave API Integration]

🛠 Technology Stack & Web Infrastructure

Database Management Systems:

• Rave (EDC)
• Oracle
• SQL Server
• MySQL
• 📝 Enhancement Note: The candidate should have experience with at least one of the listed database management systems and be willing to learn and adapt to new systems as needed.

Programming Languages & Scripts:

• SQL
• SAS
• R
• C#, C++, VBS, etc.
• PERL, etc.
• 📝 Enhancement Note: The candidate should have experience with at least one programming language and be willing to learn and adapt to new languages as needed.

CDISC Standards:

• CDASH
• SDTM
• ADaM
• 📝 Enhancement Note: The candidate should have a strong understanding of CDISC standards and be able to apply them to clinical data management processes.

Collaboration Tools:

• Microsoft Office: Word, Excel, PowerPoint, Outlook
• Jira
• Git
• 📝 Enhancement Note: The candidate should have experience with collaboration tools and be willing to learn and adapt to new tools as needed.

👥 Team Culture & Values

Clinical Data Management Values:

• Precision: Attention to detail and commitment to data quality and integrity.
• Collaboration: Effective communication and teamwork with internal stakeholders, clients, and vendors.
• Innovation: Continuous learning and adaptation to new technologies, tools, and best practices.
• Integrity: Upholding ethical standards and maintaining confidentiality and data protection.
• 📝 Enhancement Note: The candidate should demonstrate a strong commitment to these values and be able to apply them to their work in clinical data management.

Collaboration Style:

• Cross-Functional Integration: Close collaboration with internal teams, including data management, project management, and clinical operations.
• Code Review Culture: Regular review and feedback on database design, programming, and CDISC standards.
• Knowledge Sharing: Active sharing of expertise and best practices within the team and across the organization.
• 📝 Enhancement Note: The candidate should have experience working in a collaborative environment and be able to contribute to and benefit from a culture of knowledge sharing and continuous learning.

⚡ Challenges & Growth Opportunities

Technical Challenges:

• Database Optimization: Improving database performance, scalability, and efficiency.
• CDISC Standards Compliance: Ensuring data compliance with CDISC standards, including CDASH, SDTM, and ADaM.
• Stakeholder Management: Effectively communicating with internal teams, clients, and vendors to gather requirements and provide status updates.
• 📝 Enhancement Note: These challenges require a strong technical background in clinical data management, as well as excellent communication and leadership skills.

Learning & Development Opportunities:

• Technical Skills Development: Expanding expertise in programming languages, database management systems, and CDISC standards.
• Leadership Development: Developing skills in team management, project leadership, and strategic decision-making.
• Career Transition: Transitioning into a more specialized or senior role within the organization, such as a Director or Vice President of Clinical Data Management.
• 📝 Enhancement Note: Learning and development opportunities are tailored to the individual's skills, interests, and career goals, with a focus on continuous learning and professional development.

💡 Interview Preparation

Technical Questions:

• Database Design: Questions focusing on database design principles, including normalization, indexing, and optimization.
• Programming: Questions focusing on programming languages and scripts relevant to the role, such as SQL, SAS, and R.
• CDISC Standards: Questions focusing on CDISC standards, including CDASH, SDTM, and ADaM.
• Stakeholder Communication: Questions focusing on effective communication with internal teams, clients, and vendors.
• 📝 Enhancement Note: Technical questions are designed to assess the candidate's technical expertise and their ability to apply it to real-world scenarios in clinical data management.

Company & Culture Questions:

• Company Culture: Questions focusing on the candidate's understanding of Precision Medicine Group's culture, values, and mission.
• Team Dynamics: Questions focusing on the candidate's ability to work effectively within a team and collaborate with internal stakeholders.
• Career Goals: Questions focusing on the candidate's long-term career goals and how they align with the role and the organization.
• 📝 Enhancement Note: Company and culture questions are designed to assess the candidate's cultural fit within the organization and their potential for long-term success in the role.

Portfolio Presentation Strategy:

• Project Selection: Choose projects that demonstrate the candidate's experience in clinical data management, database development, and programming.
• Case Study Structure: Organize projects into clear, structured case studies, highlighting the problem, solution, and outcome.
• Technical Documentation: Include detailed technical documentation, demonstrating the candidate's ability to manage complex projects and ensure data quality and integrity.
• 📝 Enhancement Note: The portfolio presentation strategy should showcase the candidate's ability to manage complex projects, collaborate with stakeholders, and ensure data quality and integrity.

📌 Application Steps

To apply for this Senior/Principal Clinical Database Manager position:

• Submit your application through the application link.
• Prepare a portfolio showcasing your experience in clinical data management, database development, and programming.
• Brush up on your technical skills, focusing on database design, programming, and CDISC standards.
• Research Precision Medicine Group's culture, values, and mission.
• 📝 Enhancement Note: The application process is designed to assess the candidate's technical expertise, communication skills, and cultural fit within the organization.