📍 Job Overview

Job Title: Senior/Principal Clinical Database Manager
Company: Precision for Medicine
Location: Remote (UK, Spain, Hungary, Poland, Romania, Serbia, Slovakia)
Job Type: Full-Time
Category: Data Management, Clinical Research
Date Posted: 2025-08-01
Experience Level: 5-10 years
Remote Status: Remote Solely

🚀 Role Summary

Lead the design, development, testing, implementation, maintenance, and support of clinical databases and applications.
Collaborate with internal teams, clients, and vendors to gather requirements and provide status updates.
Provide operational and technical training to end users and junior staff.
Potentially lead internal software projects requiring specialized programming and/or scripting.
📝 Enhancement Note: This role requires a strong technical background in clinical data management, with a focus on database development and programming. Experience in a clinical, scientific, or healthcare discipline is also crucial for success in this position.

💻 Primary Responsibilities

Database Management: Design, develop, test, implement, maintain, and support clinical databases and applications.
Stakeholder Communication: Interface directly with internal teams, clients, and vendors to gather requirements and provide status updates.
Training: Provide operational and technical training to end users and junior staff.
Project Leadership: Potentially lead internal software projects requiring specialized programming and/or scripting.
📝 Enhancement Note: This role requires strong leadership and interpersonal skills to effectively communicate with various stakeholders and manage projects.

🎓 Skills & Qualifications

Education: Bachelor’s degree or a combination of related experience.

Experience: Minimum of 5-10 years of experience in developing and customizing clinical data management databases in a clinical, scientific, or health care discipline.

Required Skills:

Proficiency in Microsoft Office: Word, Excel, PowerPoint, Outlook.
Excellent organizational and communication skills.
Professional use of the English language, both written and oral.
Experience in Object Oriented Programming (C#, C++, VBS, etc.…), scripting language (PERL, etc.), SAS, R, SQL.
Understanding of CDISC standards (CDASH, SDTM, ADaM, etc.).
Experience in clinical database management system development.
Experience in utilizing various clinical database management systems.
Broad knowledge of drug, device, and/or biologic development and effective data management practices.
Strong leadership and interpersonal skills.
Must be able to communicate effectively in the English language.
📝 Enhancement Note: Experience in oncology and/or orphan drug therapeutic areas is preferred but not required.

Preferred Skills:

Base SAS®, SAS/STAT and SAS/ACCESS software.
SAS Macro programming language.
Advanced experience in Database Management, object-oriented programming.
Veeva set up experience.

📊 Web Portfolio & Project Requirements

Portfolio Essentials:

Demonstrate experience in developing and customizing clinical data management databases.
Showcase proficiency in programming languages and understanding of CDISC standards.
Highlight experience in utilizing various clinical database management systems.
📝 Enhancement Note: A portfolio showcasing successful clinical database management projects, with a focus on user experience and data integrity, would be beneficial for this role.

Technical Documentation:

Provide examples of technical documentation, such as data management plans, database design documents, and code comments.
📝 Enhancement Note: Candidates should emphasize their ability to document technical aspects clearly and concisely, ensuring that their work is understandable to both technical and non-technical stakeholders.

💵 Compensation & Benefits

Salary Range: £60,000 - £80,000 per annum (approximate, based on UK market rates for similar roles)

Benefits:

Competitive benefits package, including health, dental, and vision insurance.
Retirement savings plan with company match.
Generous time off, including vacation, sick, and holiday leave.
Employee assistance program.
📝 Enhancement Note: The salary range provided is an estimate based on market research for similar roles in the UK. Actual compensation may vary depending on the candidate's experience, skills, and location.

Working Hours: Full-time, typically 40 hours per week, with flexibility for project demands.

🎯 Team & Company Context

Company Culture:

Precision for Medicine is a global leader in precision medicine, focused on revolutionizing the attack on cancer by striking tumors on a molecular level using biomarkers.
The company combines deep science with deep data from advanced technological platforms and specialized expertise in the design and execution of targeted, adaptive clinical trials.
📝 Enhancement Note: Candidates should be passionate about harnessing the power of precision medicine to optimize the oncology development pathway.

Team Structure:

The team consists of data management professionals, project managers, and other internal stakeholders who collaborate to gather requirements and provide status updates.
The role will interface directly with these teams, as well as with clients and vendors.
📝 Enhancement Note: This role requires strong collaboration and communication skills to work effectively with diverse teams and stakeholders.

Development Methodology:

The team follows Agile methodologies, with a focus on iterative development, continuous improvement, and regular status updates.
📝 Enhancement Note: Candidates should be comfortable working in an Agile environment and contributing to the continuous improvement of clinical data management processes.

Company Website: Precision for Medicine

📈 Career & Growth Analysis

Web Technology Career Level: Senior/Principal level, with a focus on technical leadership and project management in clinical data management.

Reporting Structure: This role reports directly to the Head of Data Management or a similar senior-level position.

Technical Impact: The Senior/Principal Clinical Database Manager has a significant impact on the design, development, and maintenance of clinical databases and applications, ensuring data integrity and user experience.

Growth Opportunities:

Career Progression: Opportunities for career progression into more senior roles, such as Director or Vice President of Data Management.
Technical Skill Development: Opportunities to develop advanced skills in programming, scripting, and database management, as well as exposure to emerging technologies in the precision medicine field.
Technical Leadership: Opportunities to mentor junior staff and contribute to the development of best practices in clinical data management.
📝 Enhancement Note: Candidates should be proactive in seeking out growth opportunities and demonstrating their commitment to continuous learning and development.

🌐 Work Environment

Office Type: Remote work environment, with the option to work from home or a co-working space.

Office Location(s): Remote work is available for candidates based in the UK, Spain, Hungary, Poland, Romania, Serbia, or Slovakia.

Workspace Context:

Remote Work: Candidates should have a dedicated workspace with reliable internet access and a suitable working environment for remote collaboration.
Communication Tools: The team uses various communication tools, such as email, instant messaging, and video conferencing, to facilitate remote collaboration.
📝 Enhancement Note: Candidates should be comfortable working in a remote environment and have the necessary tools and resources to succeed in this setting.

Work Schedule: Full-time, typically 40 hours per week, with flexibility for project demands and maintenance windows.

📄 Application & Technical Interview Process

Interview Process:

Phone/Video Screen: A brief conversation to assess communication skills and cultural fit.
Technical Assessment: A hands-on assessment of the candidate's technical skills, focusing on database development, programming, and scripting.
Behavioral Interview: An in-depth discussion of the candidate's experience, leadership skills, and problem-solving abilities.
Final Interview: A meeting with senior leadership to discuss the candidate's fit for the role and the organization.

📝 Enhancement Note: Candidates should prepare for behavioral interview questions that focus on their experience with clinical data management, stakeholder communication, and project leadership.

Portfolio Review Tips:

Highlight successful clinical database management projects, with a focus on user experience and data integrity.
Include examples of technical documentation, such as data management plans, database design documents, and code comments.
📝 Enhancement Note: Candidates should emphasize their ability to document technical aspects clearly and concisely, ensuring that their work is understandable to both technical and non-technical stakeholders.

Technical Challenge Preparation:

Brush up on programming and scripting skills, with a focus on object-oriented programming, SAS, R, and SQL.
Familiarize oneself with CDISC standards and clinical database management systems.
📝 Enhancement Note: Candidates should practice explaining technical concepts clearly and concisely, ensuring that their communication is accessible to both technical and non-technical stakeholders.

ATS Keywords: [Clinical Data Management, Database Development, Programming, Scripting, CDISC Standards, SAS, R, SQL, Stakeholder Communication, Project Leadership, Oncology, Orphan Drugs, Veeva, Microsoft Office, Data Management Practices, Technical Training]

🛠 Technology Stack & Web Infrastructure

Database Technologies:

Experience with various clinical database management systems is required.
Proficiency in Object Oriented Programming (C#, C++, VBS, etc.…), scripting language (PERL, etc.), SAS, R, SQL.
📝 Enhancement Note: Candidates should be comfortable working with a variety of database technologies and have experience in clinical database management system development.

Development & DevOps Tools:

Proficiency in Microsoft Office: Word, Excel, PowerPoint, Outlook.
Experience with Base SAS®, SAS/STAT and SAS/ACCESS software, SAS Macro programming language, and advanced experience in Database Management, object-oriented programming is preferred but not required.
📝 Enhancement Note: Candidates should be comfortable working with a variety of development and DevOps tools, with a focus on database management and programming.

👥 Team Culture & Values

Web Development Values:

Precision Medicine: A passion for harnessing the power of precision medicine to optimize the oncology development pathway.
Collaboration: Strong leadership and interpersonal skills to effectively communicate with various stakeholders and manage projects.
Continuous Learning: A commitment to continuous learning and development in the field of clinical data management.
📝 Enhancement Note: Candidates should be passionate about precision medicine and committed to continuous learning and development in the field of clinical data management.

Collaboration Style:

Cross-Functional Integration: Collaboration with internal teams, clients, and vendors to gather requirements and provide status updates.
Code Review: Regular code reviews to ensure data integrity and user experience.
Knowledge Sharing: A culture of knowledge sharing and technical mentoring to support the development of junior staff.
📝 Enhancement Note: Candidates should be comfortable working in a collaborative environment and contributing to the development of best practices in clinical data management.

⚡ Challenges & Growth Opportunities

Technical Challenges:

Database Development: Designing, developing, testing, implementing, maintaining, and supporting clinical databases and applications.
Stakeholder Communication: Interfacing directly with internal teams, clients, and vendors to gather requirements and provide status updates.
Project Leadership: Potentially leading internal software projects requiring specialized programming and/or scripting.
📝 Enhancement Note: Candidates should be proactive in seeking out technical challenges and demonstrating their commitment to continuous learning and development in the field of clinical data management.

Learning & Development Opportunities:

Career Progression: Opportunities for career progression into more senior roles, such as Director or Vice President of Data Management.
Technical Skill Development: Opportunities to develop advanced skills in programming, scripting, and database management, as well as exposure to emerging technologies in the precision medicine field.
Technical Mentorship: Opportunities to mentor junior staff and contribute to the development of best practices in clinical data management.
📝 Enhancement Note: Candidates should be proactive in seeking out learning and development opportunities and demonstrating their commitment to continuous learning and development in the field of clinical data management.

💡 Interview Preparation

Technical Questions:

Database Development: Questions focusing on the candidate's experience with clinical database management systems, programming, and scripting.
Stakeholder Communication: Questions assessing the candidate's ability to communicate effectively with internal teams, clients, and vendors.
Project Leadership: Questions evaluating the candidate's leadership skills and experience managing projects.
📝 Enhancement Note: Candidates should prepare for technical questions that focus on their experience with clinical data management, stakeholder communication, and project leadership.

Company & Culture Questions:

Precision Medicine: Questions assessing the candidate's passion for harnessing the power of precision medicine to optimize the oncology development pathway.
Collaboration: Questions evaluating the candidate's ability to work effectively in a collaborative environment and contribute to the development of best practices in clinical data management.
Continuous Learning: Questions focusing on the candidate's commitment to continuous learning and development in the field of clinical data management.
📝 Enhancement Note: Candidates should prepare for company and culture questions that focus on their passion for precision medicine, collaboration, and continuous learning and development in the field of clinical data management.

Portfolio Presentation Strategy:

Project Case Studies: Highlight successful clinical database management projects, with a focus on user experience and data integrity.
Technical Documentation: Include examples of technical documentation, such as data management plans, database design documents, and code comments.
📝 Enhancement Note: Candidates should emphasize their ability to document technical aspects clearly and concisely, ensuring that their work is understandable to both technical and non-technical stakeholders.

📌 Application Steps

To apply for this Senior/Principal Clinical Database Manager position:

Submit your application through the application link provided on the job posting.
Prepare a portfolio showcasing successful clinical database management projects, with a focus on user experience and data integrity.
Tailor your resume to highlight your experience with clinical data management, stakeholder communication, and project leadership.
Prepare for technical and behavioral interviews by reviewing the interview process outlined above and practicing your responses to common interview questions.
Research the company and its precision medicine focus to ensure a strong cultural fit.

⚠️ Important Notice: This enhanced job description includes AI-generated insights and clinical data management industry-standard assumptions. All details should be verified directly with the hiring organization before making application decisions.

Senior/Principal Clinical Database Manager