📍 Job Overview

Job Title: Senior/Principal Clinical Database Manager
Company: Precision for Medicine
Location: Remote, United Kingdom
Job Type: Full-Time
Category: Clinical Data Management
Date Posted: 2025-08-01
Experience Level: 5-10 years
Remote Status: Remote Solely

🚀 Role Summary

Lead the design, development, and maintenance of clinical databases and applications
Collaborate with internal teams, clients, and vendors to gather requirements and provide status updates
Provide operational and technical training to end users and junior staff
Play a lead role in internal software projects requiring specialized programming and/or scripting
Demonstrate strong leadership, interpersonal, and communication skills
Possess a broad knowledge of drug, device, and biologic development and effective data management practices

📝 Enhancement Note: This role requires a unique blend of technical expertise in clinical database management and strong leadership skills to manage cross-functional teams and stakeholders.

💻 Primary Responsibilities

Clinical Database Management: Design, develop, test, implement, maintain, and support clinical databases and applications
Stakeholder Communication: Interface with internal teams, clients, and vendors to gather requirements and provide status updates
Training and Mentoring: Provide operational and technical training to end users and junior staff
Project Leadership: Lead internal software projects requiring specialized programming and/or scripting
Team Collaboration: Work closely with data management, project management, and other internal teams to ensure project success
Problem-Solving: Troubleshoot and resolve technical issues related to clinical databases and applications

📝 Enhancement Note: The successful candidate will have a proven track record of managing complex clinical database projects, with a strong focus on data quality, accuracy, and timeliness.

🎓 Skills & Qualifications

Education: Bachelor’s degree in a relevant field or a combination of related experience

Experience: Minimum of 5-10 years of experience in developing and customizing clinical data management databases in a clinical, scientific, or healthcare discipline

Required Skills:

Proficiency in Microsoft Office (Word, Excel, PowerPoint, Outlook)
Experience with Rave API integration and Rave Advanced Custom Function programming
Object-Oriented Programming (C#, C++, VBS, etc.)
Scripting language (PERL, etc.)
SAS, R, SQL
Understanding of CDISC standards (CDASH, SDTM, ADaM, etc.)
Experience in clinical database management system development
Experience in a clinical, scientific, or healthcare discipline
Experience utilizing various clinical database management systems
Excellent organizational and communication skills
Professional use of the English language, both written and oral

Preferred Skills:

Oncology and/or Orphan Drug therapeutic experience
Base SAS®, SAS/STAT and SAS/ACCESS software
SAS Macro programming language
Advanced experience in Database Management, object-oriented programming
Veeva set up experience

📝 Enhancement Note: Candidates with experience in oncology and/or orphan drug therapeutics, as well as advanced SAS and database management skills, will have a competitive advantage in this role.

📊 Web Portfolio & Project Requirements

Portfolio Essentials:

Demonstrate a strong portfolio showcasing clinical database management projects, highlighting your technical expertise and problem-solving skills
Include case studies that illustrate your ability to manage complex projects, collaborate with stakeholders, and deliver high-quality results
Showcase your proficiency in programming languages, scripting, and CDISC standards through code samples and project documentation

Technical Documentation:

Provide detailed technical documentation for your clinical database management projects, including data models, database schemas, and code comments
Include performance metrics, testing methodologies, and optimization techniques used in your projects
Demonstrate your understanding of data privacy, security, and compliance regulations relevant to clinical data management

📝 Enhancement Note: A well-structured portfolio that emphasizes your technical skills, problem-solving abilities, and attention to detail will be crucial for success in this role.

💵 Compensation & Benefits

Salary Range: £60,000 - £80,000 per annum (based on UK market rates for senior clinical data management roles)

Benefits:

Competitive salary and benefits package
Opportunities for professional development and growth
Collaborative and inclusive work environment
Flexible remote work arrangement

Working Hours: Full-time, 40 hours per week, with flexibility for project deadlines and maintenance windows

📝 Enhancement Note: The salary range provided is an estimate based on market research for senior clinical data management roles in the UK. The actual salary may vary depending on the candidate's experience, skills, and the company's internal salary structure.

🎯 Team & Company Context

🏢 Company Culture

Industry: Precision Medicine and Oncology

Company Size: Medium to Large (1,001-5,000 employees)

Founded: 2012

Team Structure:

Collaborative and cross-functional teams, including data management, project management, and other internal teams
Flat hierarchy with a focus on empowerment and autonomy
Strong emphasis on data-driven decision-making and continuous improvement

Development Methodology:

Agile and iterative development processes
Regular team meetings and stand-ups to ensure project progress and alignment
Strong focus on data quality, accuracy, and timeliness

Company Website: Precision for Medicine

📝 Enhancement Note: Precision for Medicine is a leading provider of precision medicine and oncology services, with a strong focus on data-driven insights and real-world evidence. The company's culture emphasizes collaboration, innovation, and a patient-centric approach to drug development.

📈 Career & Growth Analysis

Clinical Data Management Career Level: Senior/Principal Clinical Database Manager

Reporting Structure: Reports directly to the Head of Data Management or a similar role, with matrixed relationships to other internal teams and stakeholders

Technical Impact: Responsible for the design, development, and maintenance of clinical databases and applications that support drug development and clinical trials

Growth Opportunities:

Technical Growth: Expand your expertise in clinical database management, programming languages, and emerging technologies
Leadership Growth: Develop your leadership and mentoring skills by guiding junior staff and cross-functional teams
Career Progression: Transition into roles such as Head of Data Management, Director of Clinical Data Management, or other senior leadership positions within the company or the broader precision medicine industry

📝 Enhancement Note: The Senior/Principal Clinical Database Manager role offers significant opportunities for technical and leadership growth, as well as the potential for career progression within the precision medicine industry.

🌐 Work Environment

Office Type: Remote, with occasional in-person meetings and team-building events

Office Location(s): Remote work from home or a preferred location within the specified regions

Workspace Context:

Remote work environment with the necessary tools and resources to perform the job effectively
Collaborative and inclusive team culture, with a focus on open communication and knowledge sharing
Opportunities for professional development and growth through training, mentoring, and project-based learning

Work Schedule: Full-time, 40 hours per week, with flexibility for project deadlines and maintenance windows

📝 Enhancement Note: The remote work environment offers a high degree of flexibility and autonomy, allowing candidates to balance their personal and professional lives effectively.

📄 Application & Technical Interview Process

Interview Process:

Phone Screen: A brief phone or video call to assess communication skills, cultural fit, and basic technical competencies
Technical Assessment: A hands-on technical assessment to evaluate programming, scripting, and database management skills
Behavioral Interview: A structured interview to assess problem-solving skills, leadership potential, and cultural fit
Final Interview: A final interview with senior leadership to discuss career growth, company culture, and next steps

Portfolio Review Tips:

Highlight your most relevant clinical database management projects and the technical challenges you've overcome
Include case studies that demonstrate your ability to manage complex projects, collaborate with stakeholders, and deliver high-quality results
Showcase your proficiency in programming languages, scripting, and CDISC standards through code samples and project documentation

Technical Challenge Preparation:

Brush up on your programming, scripting, and database management skills, with a focus on CDISC standards and clinical data management best practices
Prepare for behavioral interview questions that assess your problem-solving skills, leadership potential, and cultural fit
Research the company's mission, values, and recent projects to demonstrate your enthusiasm and understanding of the precision medicine industry

ATS Keywords: [Clinical Data Management, Database Development, Programming, Scripting, CDISC Standards, Oncology, Precision Medicine, Remote Work, Leadership, Stakeholder Communication, Project Management]

📝 Enhancement Note: The interview process for this role is designed to assess both technical competencies and cultural fit, with a strong emphasis on problem-solving skills, leadership potential, and communication abilities.

🛠 Technology Stack & Web Infrastructure

Database Management Systems:

Rave (EDC)
SAS
SQL Server
Oracle
PostgreSQL

Programming Languages:

C#
C++
VBScript
Perl
Python
R

Scripting Languages:

SAS Macro
SQL
Perl
Python

Other Tools:

Microsoft Office (Word, Excel, PowerPoint, Outlook)
Veeva Vault
CDISC Standards (CDASH, SDTM, ADaM)

📝 Enhancement Note: The technology stack for this role includes a mix of proprietary and open-source tools, with a strong emphasis on clinical data management, programming, and scripting languages.

👥 Team Culture & Values

Clinical Data Management Values:

Patient-Centric: Focus on improving patient outcomes through data-driven insights and real-world evidence
Data-Driven: Emphasize data quality, accuracy, and timeliness in all aspects of clinical data management
Collaborative: Foster a culture of open communication, knowledge sharing, and teamwork
Innovative: Encourage continuous learning, improvement, and the adoption of emerging technologies

Collaboration Style:

Cross-Functional: Work closely with internal teams, clients, and vendors to gather requirements and provide status updates
Iterative: Use agile and iterative development processes to ensure project progress and alignment
Inclusive: Foster a culture of open communication, knowledge sharing, and teamwork

📝 Enhancement Note: Precision for Medicine's clinical data management team values a patient-centric, data-driven, and collaborative approach to drug development and clinical trials. The team fosters a culture of open communication, knowledge sharing, and continuous improvement.

⚡ Challenges & Growth Opportunities

Technical Challenges:

Managing complex clinical database projects with tight deadlines and competing priorities
Troubleshooting and resolving technical issues related to clinical databases and applications
Staying up-to-date with emerging technologies, programming languages, and CDISC standards

Learning & Development Opportunities:

Technical Skills: Expand your expertise in clinical database management, programming languages, and emerging technologies
Leadership Skills: Develop your leadership and mentoring skills by guiding junior staff and cross-functional teams
Career Progression: Transition into roles such as Head of Data Management, Director of Clinical Data Management, or other senior leadership positions within the company or the broader precision medicine industry
Industry Knowledge: Stay up-to-date with the latest trends, best practices, and regulatory requirements in precision medicine and oncology

📝 Enhancement Note: The Senior/Principal Clinical Database Manager role presents significant technical challenges and learning opportunities, with a strong emphasis on continuous growth and development.

💡 Interview Preparation

Technical Questions:

Programming & Scripting: Describe your experience with programming languages, scripting, and database management systems in the context of clinical data management
CDISC Standards: Explain your understanding of CDISC standards (CDASH, SDTM, ADaM) and their application in clinical database management
Project Management: Discuss your experience with project management, stakeholder communication, and team collaboration in clinical data management projects

Company & Culture Questions:

Precision Medicine: Demonstrate your understanding of precision medicine and its application in drug development and clinical trials
Oncology: Showcase your knowledge of oncology and its specific data management challenges and opportunities
Company Culture: Explain why you are a good fit for Precision for Medicine's collaborative, data-driven, and patient-centric culture

Portfolio Presentation Strategy:

Project Selection: Choose your most relevant clinical database management projects that showcase your technical skills, problem-solving abilities, and attention to detail
Storytelling: Craft compelling narratives that highlight the challenges you faced, the solutions you implemented, and the outcomes you achieved
Visual Aids: Use visual aids, such as diagrams, charts, and screenshots, to illustrate your technical expertise and enhance your presentation

📝 Enhancement Note: The interview process for this role is designed to assess both technical competencies and cultural fit, with a strong emphasis on problem-solving skills, leadership potential, and communication abilities.

📌 Application Steps

To apply for this Senior/Principal Clinical Database Manager position:

Review the Job Description: Thoroughly read and understand the job description, highlighting the key responsibilities, required skills, and preferred qualifications
Tailor Your Resume: Customize your resume to emphasize your relevant experience, skills, and achievements in clinical data management, programming, scripting, and database management
Prepare Your Portfolio: Curate a strong portfolio showcasing your clinical database management projects, programming and scripting skills, and attention to detail
Research the Company: Familiarize yourself with Precision for Medicine's mission, values, and recent projects to demonstrate your enthusiasm and understanding of the precision medicine industry
Practice Interview Questions: Prepare for technical and behavioral interview questions that assess your problem-solving skills, leadership potential, and cultural fit
Apply: Submit your application through the application link provided, including your resume, portfolio, and any other required documents

⚠️ Important Notice: This enhanced job description includes AI-generated insights and clinical data management industry-standard assumptions. All details should be verified directly with the hiring organization before making application decisions.

Senior/Principal Clinical Database Manager