📍 Job Overview

Job Title: Principal Manufacturing Systems Engineer - Amgen Dun Laoghaire Project Delivery Lead
Company: Amgen
Location: Dublin, Ireland
Job Type: On-site
Category: Engineering
Date Posted: June 19, 2025
Experience Level: Mid-Senior level (5-10 years)
Remote Status: On-site

🚀 Role Summary

Lead the execution and delivery of a portfolio of IS/Automation projects, driving digital innovation in manufacturing processes.
Build and develop high-performing teams to support projects across Amgen's manufacturing plants, with a focus on the Dun Laoghaire facility.
Collaborate with cross-functional teams, stakeholders, and vendors to ensure successful project delivery and implementation.

📝 Enhancement Note: This role offers an exciting opportunity to drive technological advancements in manufacturing, contributing to Amgen's mission of serving patients and improving lives.

💻 Primary Responsibilities

Project Portfolio Management: Lead the execution and successful delivery of a varied portfolio of IS/Automation projects, managing resources, risks, and finances effectively.
End-to-End Project Delivery: Accountable for projects from business case creation to qualification and go-live into manufacturing production, including scope definition, technical leadership, budget management, and vendor engagement.
Cross System Analysis & Problem Solving: Perform cross-system analysis, feasibility analysis, and scope projects, prioritizing deliverables and recommending optimal solutions.
Stakeholder Communication & Relationship Management: Effectively communicate with multiple levels within the organization, highlighting issues, and proposing solutions. Manage relationships with peers, IS service owners, business partners, enterprise IS service partners, and vendors.
Functional Design & Technical Leadership: Accountable to elicit and analyze needs identified by business stakeholders and convert them into functional design. Provide technical leadership and apply corporate blueprint and standards using business drivers to local business needs and project requirements.

📝 Enhancement Note: This role requires a strong project management background, with the ability to anticipate, evaluate, and resolve multiple, simultaneous project issues, delays, and problems.

🎓 Skills & Qualifications

Education: Doctorate, Master's, or Bachelor's degree in Engineering with a focus on Information Systems, Computer Science, or a related field.

Experience: 5-10 years of combined Information Systems and Manufacturing Process Automation experience, with a preference for experience in the GMP-regulated industry and the Pharma/Biotech sector.

Required Skills:

Project Management
Technical Leadership
Budget Management
Risk Management
Automation
Information Systems
Manufacturing Process
Cross System Analysis
Vendor Engagement
Stakeholder Communication
Feasibility Analysis
Scope Definition
Team Building
Digital Innovation
Problem Solving
Strategic Planning

Preferred Skills:

Experience in the GMP-regulated industry
Strong manufacturing background, particularly in the Pharma/Biotech sector
Experience leading projects and resources in a manufacturing environment

📝 Enhancement Note: Candidates with a strong background in manufacturing, information systems, and project management will excel in this role.

📊 Web Portfolio & Project Requirements

Portfolio Essentials:

Demonstrate successful project delivery in a manufacturing environment, highlighting your ability to manage resources, risks, and finances.
Showcase your technical leadership and problem-solving skills through case studies or project examples.
Highlight your experience with cross-system analysis, feasibility analysis, and scope definition.

Technical Documentation:

Provide detailed project documentation, including business cases, technical specifications, and risk assessments.
Include information on vendor engagement, stakeholder communication, and project outcomes.
Demonstrate your understanding of corporate blueprint and standards, and how you've applied them to local business needs and project requirements.

📝 Enhancement Note: A strong portfolio will showcase your ability to deliver complex projects, manage stakeholders, and drive digital innovation in manufacturing.

💵 Compensation & Benefits

Salary Range: €85,000 - €110,000 per year (based on market research for mid-senior level engineering roles in Dublin, Ireland)

Benefits:

Competitive salary and benefits package
Comprehensive health insurance
Retirement savings plan with company match
Employee stock purchase plan
Generous time off and leave policies
On-site amenities and wellness programs
Opportunities for professional development and career growth

Working Hours: Full-time, typically 40 hours per week, with flexibility for project deadlines and maintenance windows.

📝 Enhancement Note: Salary range is estimated based on market research for mid-senior level engineering roles in Dublin, Ireland, with adjustments for cost of living.

🎯 Team & Company Context

🏢 Company Culture

Industry: Biopharmaceutical manufacturing and research

Company Size: Large (over 20,000 employees)

Founded: 1980

Team Structure:

The Principal Manufacturing Systems Engineer will lead a team of project delivery professionals, collaborating with cross-functional teams, stakeholders, and vendors.
The role will work closely with the manufacturing operations team, ensuring that projects align with business needs and support the plant's production goals.

Development Methodology:

Amgen follows a structured project management approach, utilizing tools and methodologies to ensure project success.
The role will apply Agile principles to manage project portfolios, with a focus on delivering value to the business and driving continuous improvement.

Company Website: Amgen

📝 Enhancement Note: Amgen's company culture emphasizes innovation, collaboration, and a commitment to serving patients. The company's focus on biopharmaceutical manufacturing and research provides a unique opportunity for the Principal Manufacturing Systems Engineer to drive digital innovation in the industry.

📈 Career & Growth Analysis

Web Technology Career Level: Mid-Senior level (5-10 years of experience)

Reporting Structure: The Principal Manufacturing Systems Engineer will report directly to the Site Director of Manufacturing Operations or a designated senior leader within the organization.

Technical Impact: This role will have a significant impact on Amgen's manufacturing processes, driving digital innovation and improving operational efficiency. The Principal Manufacturing Systems Engineer will play a crucial role in shaping the company's Industry 4.0 capabilities and supporting the plant's production goals.

Growth Opportunities:

Technical Growth: Develop expertise in manufacturing automation, information systems, and project management. Stay up-to-date with emerging technologies and industry trends to drive continuous improvement.
Leadership Growth: Build and develop high-performing teams, mentoring team members and fostering a culture of collaboration and innovation. Explore opportunities for technical leadership and architecture decision-making.
Career Progression: Pursue opportunities for career advancement within Amgen's global organization, such as roles in senior project management, technical leadership, or operations management.

📝 Enhancement Note: The Principal Manufacturing Systems Engineer role offers significant growth opportunities, both in terms of technical expertise and career advancement. Candidates with a strong desire to learn, adapt, and drive innovation will thrive in this role.

🌐 Work Environment

Office Type: On-site, with opportunities for remote work and flexible scheduling

Office Location(s): Amgen's manufacturing plant in Dun Laoghaire, Ireland, with potential support for projects at other Amgen facilities.

Workspace Context:

The Principal Manufacturing Systems Engineer will work in an on-site office environment, collaborating with cross-functional teams and stakeholders.
The role may require travel to other Amgen facilities or vendor sites, as needed.
Amgen offers a modern, collaborative work environment with state-of-the-art facilities and on-site amenities.

Work Schedule: Full-time, typically 40 hours per week, with flexibility for project deadlines and maintenance windows. Amgen offers a flexible work arrangement, allowing employees to balance their work and personal lives.

📝 Enhancement Note: Amgen's work environment fosters collaboration, innovation, and a commitment to serving patients. The Principal Manufacturing Systems Engineer will have the opportunity to work in a dynamic, fast-paced environment that supports the company's mission and production goals.

📄 Application & Technical Interview Process

Interview Process:

Phone or Video Screen: A brief conversation to assess your qualifications, experience, and fit for the role.
Technical Interview: A deeper dive into your technical skills, project management experience, and understanding of manufacturing processes. Be prepared to discuss your approach to cross-system analysis, feasibility analysis, and scope definition.
Behavioral Interview: Assess your problem-solving skills, communication abilities, and cultural fit with Amgen's values and mission.
Final Interview: Meet with senior leadership to discuss your career aspirations, growth opportunities, and fit for the role.

Portfolio Review Tips:

Highlight your successful project delivery in a manufacturing environment, demonstrating your ability to manage resources, risks, and finances.
Showcase your technical leadership and problem-solving skills through case studies or project examples.
Emphasize your experience with cross-system analysis, feasibility analysis, and scope definition.

Technical Challenge Preparation:

Brush up on your project management skills, focusing on portfolio planning, resource management, and risk management.
Familiarize yourself with Amgen's company culture, values, and mission to demonstrate your cultural fit and commitment to serving patients.
Prepare for questions about your approach to stakeholder communication, vendor engagement, and driving digital innovation in manufacturing.

ATS Keywords: (Organized by category)

Project Management: Project Portfolio Management, Resource Management, Risk Management, Budget Management, Project Delivery, Project Planning, Project Lifecycle, Stakeholder Management, Vendor Management
Manufacturing: Manufacturing Process, Manufacturing Operations, Industry 4.0, Automation, GMP-regulated Industry, Pharma/Biotech Sector
Technical Skills: Cross System Analysis, Feasibility Analysis, Scope Definition, Technical Leadership, Functional Design, Corporate Blueprint, Standards Application
Soft Skills: Communication, Collaboration, Problem Solving, Strategic Planning, Innovation, Team Building

📝 Enhancement Note: The interview process for the Principal Manufacturing Systems Engineer role will focus on assessing your technical skills, project management experience, and cultural fit with Amgen's values and mission. Prepare for a comprehensive evaluation of your qualifications and experience.

🛠 Technology Stack & Web Infrastructure

Project Management Tools: (Preferred, but not limited to)

Microsoft Project
Jira
Asana
Trello

Manufacturing Software: (Preferred, but not limited to)

Manufacturing Execution Systems (MES)
Enterprise Resource Planning (ERP) systems
Supervisory Control and Data Acquisition (SCADA) systems
Computerized Maintenance Management Systems (CMMS)

Information Systems: (Preferred, but not limited to)

Enterprise Resource Planning (ERP) systems
Customer Relationship Management (CRM) systems
Business Intelligence (BI) tools
Data analytics and visualization tools

📝 Enhancement Note: The Principal Manufacturing Systems Engineer will work with a variety of project management, manufacturing, and information systems to drive digital innovation and improve operational efficiency. Familiarity with these tools and systems is preferred but not required.

👥 Team Culture & Values

Amgen's Values:

Patients First
Quality
Integrity
Collaboration
Inclusion
Courage
Accountability

Web Development Values:

Patient Focus: Prioritize projects and solutions that directly impact patients and improve their lives.
Innovation: Embrace emerging technologies and industry trends to drive digital innovation in manufacturing.
Collaboration: Work closely with cross-functional teams, stakeholders, and vendors to ensure project success.
Quality: Deliver high-quality projects that meet business needs and support Amgen's production goals.
Continuous Learning: Stay up-to-date with industry trends and best practices to drive continuous improvement.

Collaboration Style:

Cross-functional Integration: Work closely with manufacturing operations, quality, and other functional teams to ensure projects align with business needs and support Amgen's production goals.
Code Review Culture: Encourage open communication, active listening, and constructive feedback to drive continuous improvement.
Peer Programming: Collaborate with team members and stakeholders to ensure projects are delivered on time, within budget, and to the required quality standards.

📝 Enhancement Note: Amgen's culture emphasizes patient focus, innovation, collaboration, and continuous learning. The Principal Manufacturing Systems Engineer will play a crucial role in driving digital innovation and improving operational efficiency, aligning with the company's values and mission.

⚡ Challenges & Growth Opportunities

Technical Challenges:

Project Complexity: Manage multiple, simultaneous projects with varying scopes, timelines, and priorities.
Stakeholder Management: Balance the needs and expectations of multiple stakeholders, including business partners, enterprise IS service partners, and vendors.
Emerging Technologies: Stay up-to-date with emerging technologies and industry trends, and apply them to drive digital innovation in manufacturing.
Operational Efficiency: Continuously improve manufacturing processes, reducing waste, and enhancing productivity.

Learning & Development Opportunities:

Technical Skill Development: Enhance your expertise in manufacturing automation, information systems, and project management through training, workshops, and on-the-job experiences.
Leadership Development: Build and develop high-performing teams, mentoring team members, and fostering a culture of collaboration and innovation.
Career Progression: Pursue opportunities for career advancement within Amgen's global organization, such as roles in senior project management, technical leadership, or operations management.

📝 Enhancement Note: The Principal Manufacturing Systems Engineer role presents numerous technical challenges and growth opportunities. Candidates with a strong desire to learn, adapt, and drive innovation will thrive in this role.

💡 Interview Preparation

Technical Questions:

Project Management: Describe your approach to project portfolio management, resource management, and risk management. Provide examples of successful project delivery in a manufacturing environment.
Manufacturing Processes: Explain your understanding of manufacturing processes, Industry 4.0 capabilities, and automation. Discuss how you've applied this knowledge to drive digital innovation and improve operational efficiency.
Stakeholder Management: Walkthrough your approach to stakeholder communication, vendor engagement, and managing multiple, simultaneous projects with varying scopes, timelines, and priorities.

Company & Culture Questions:

Amgen's Mission: Explain how you align with Amgen's mission to serve patients and improve lives. Describe how you've demonstrated this commitment in your previous roles.
Amgen's Values: Discuss how you embody Amgen's values, providing specific examples from your previous experiences.
Amgen's Culture: Describe what you like about Amgen's culture and how you believe you can contribute to the team's success.

Portfolio Presentation Strategy:

Project Delivery: Highlight your successful project delivery in a manufacturing environment, demonstrating your ability to manage resources, risks, and finances.
Technical Leadership: Showcase your technical leadership and problem-solving skills through case studies or project examples.
Stakeholder Communication: Emphasize your experience with cross-system analysis, feasibility analysis, and scope definition, and how you've effectively communicated these aspects to stakeholders.

📝 Enhancement Note: The interview process for the Principal Manufacturing Systems Engineer role will focus on assessing your technical skills, project management experience, and cultural fit with Amgen's values and mission. Prepare for a comprehensive evaluation of your qualifications and experience.

📌 Application Steps

To apply for this Principal Manufacturing Systems Engineer position:

Submit your application through the Amgen Careers website.
Portfolio Customization: Tailor your portfolio to highlight your successful project delivery in a manufacturing environment, demonstrating your ability to manage resources, risks, and finances. Include case studies or project examples that showcase your technical leadership and problem-solving skills.
Resume Optimization: Highlight your relevant experience, skills, and accomplishments in project management, manufacturing processes, and information systems. Include any experience you have working with Amgen's preferred project management, manufacturing, and information systems tools.
Technical Interview Preparation: Brush up on your project management skills, focusing on portfolio planning, resource management, and risk management. Familiarize yourself with Amgen's company culture, values, and mission to demonstrate your cultural fit and commitment to serving patients. Prepare for questions about your approach to stakeholder communication, vendor engagement, and driving digital innovation in manufacturing.
Company Research: Thoroughly research Amgen's company culture, values, and mission. Understand the company's focus on biopharmaceutical manufacturing and research, and how the Principal Manufacturing Systems Engineer role can drive digital innovation and improve operational efficiency.

⚠️ Important Notice: This enhanced job description includes AI-generated insights and industry-standard assumptions. All details should be verified directly with the hiring organization before making application decisions.

Principal Mfg Systems Engineer